Red Cell Sodium in Hyperthyroidism
نویسندگان
چکیده
منابع مشابه
Red cell cotransport activity and sodium content in black men.
Furosemide-sensitive sodium and potassium cotransport and intracellular sodium content ([Na]i) were measured in erythrocytes (red blood cells, RBCs) from a population of 90 adult black men with and without essential hypertension (EH). The mean values for sodium cotransport activity, expressed as furosemide-sensitive Na efflux (mmol/liter RBC/hr), were not significantly different among the EH pa...
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Measurements were made of the sodium outflux rate constant, (o)k(Na), and sodium influx rate constant, (i)k(Na), at varying concentrations of extracellular (Na(o)) and intracellular (Na(c)) sodium. (o)k(Na) increases with increasing [Na(o)] in the presence of extracellular potassium (K(o)) and in solutions containing ouabain. In K-free solutions which do not contain ouabain, (o)k(Na) falls as [...
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Abnormal erythrocyte Na+ transport has been reported in patients with essential hypertension and some first-degree relatives. The two major techniques now employed for estimating Na+ transport--Na+/Li+ countertransport and Na+/K+ cotransport--are rather intricate and time consuming. Furthermore, the precise nature of the transport processes being measured is not clear. We have developed a simpl...
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Red blood cells exposed to ouabain are capable of net Na outflux against an electrochemical gradient; the net outflux is inhibited by the diuretic, furosemide. In ouabain-treated cells, both the unidirectional Na outflux and the unidirectional Na influx are inhibited by furosemide. Furosemide also inhibits the ouabain-sensitive Na-Na exchange accomplished by the Na-K pump in K-free solutions. F...
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ژورنال
عنوان ژورنال: BMJ
سال: 1971
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5761.552